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Biophysical Regulation of Cell Behavior—Cross Talk between Substrate Stiffness and Nanotopography Review

Yong Yang, Kai Wang, Xiaosong Gu, Kam W. Leong

Engineering 2017, Volume 3, Issue 1, Pages 36-54 doi: 10.1016/J.ENG.2017.01.014

Abstract: These biophysical cues have therefore been applied to modulate almost all aspects of cell behavior, fromDelineation of the biophysical modulation of cell behavior is critical to the rational design of new; however, the interwoven effects of stiffness and nanotopographical cues on cell behavior have not beenHerein, we first review the effects of substrate stiffness and nanotopography on cell behavior, and thenAttempts are made to connect extracellular regulation of cell behavior with the biophysical cues.

Keywords： Extracellular matrix Stiffness Nanotopography Adhesive ligands Cell behavior

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Moisture diffusion behavior of permeable fiber-reinforced polymer composite

Jianjiang YANG, Qingsheng YANG, Lianhua MA, Wei LIU,

Frontiers of Mechanical Engineering 2010, Volume 5, Issue 3, Pages 347-352 doi: 10.1007/s11465-010-0093-y

Abstract: A unit cell approach is employed to predict the effective moisture diffusion property in fiber-reinforcedBased on a unit cell model, the calculation method for moisture diffusion coefficients is developed inTherefore, it is reliable in predicting moisture diffusion property of composite using the unit cell

Keywords： fiber-reinforced biopolymer effective diffusion coefficient unit cell finite element modeling (FEM)

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Study on Big Data-based Behavior Modification in Metro Construction

Lie-yun Ding,Sheng-yu Guo

Frontiers of Engineering Management 2015, Volume 2, Issue 2, Pages 131-136 doi: 10.15302/J-FEM-2015037

Abstract: , construction accidents frequently happen, which are significantly attributable to workers’ unsafe behaviorBehavior-based safety (BBS) is an effective method to modify workers’ unsafe behavior.This paper introduces the study on big data-based metro construction behavior modification, aiming toFirst, the behavior modification pushing mechanism based on content-based personalized recommendationSecondly, the development of behavior modification system of metro construction (BMSMC) is introduced

Keywords： big data unsafe behavior behavior modification behavior-based safety (BBS) unsafe behavior rate

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Flow behavior of non-spherical particle flowing in hopper

He TAO,Wenqi ZHONG,Baosheng JIN

Frontiers in Energy 2014, Volume 8, Issue 3, Pages 315-321 doi: 10.1007/s11708-014-0331-9

Abstract: Ellipsoidal particles flowing in the hopper were simulated by using the discrete element method (DEM), and described by the multi-element method. The contact detection algorithm and equations for ellipsoidal particle motion in hopper were developed. And the simulation results were confirmed by experiment. Additionally, the mass flow rate, pressure distribution and velocity distribution of two kinds of particles were examined. The results show that the mass flow rate of ellipsoidal particles is smaller than that of spherical particles. There is a maximum value of pressure drop at the top of the junction. Besides, the pressure drop decreases with the discharging time increasing. The velocity of spherical particle is larger than that of ellipsoidal.

Keywords： discrete element method ellipsoidal particle flow behavior hopper

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A simplified method for investigating the bending behavior of piles supporting embankments on soft ground

Frontiers of Structural and Civil Engineering Pages 1021-1032 doi: 10.1007/s11709-023-0952-3

Abstract: soil deformation mechanism and Poulos’ solution for pile–soil interaction to investigate the bending behaviorFurthermore, the effect of embedding a pile into a firm ground layer on the bending behavior was investigated

Keywords： bending behavior pile embankment soil−structure interaction failure mode

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Weakening behavior of waterproof performance in joints of shield tunnels under adjacent constructions

Frontiers of Structural and Civil Engineering Pages 884-900 doi: 10.1007/s11709-022-0912-3

Abstract: In this study, the weakening behavior of waterproof performance was investigated in the joints of shield

Keywords： shield tunnel waterproof performance horizontal transverse deformation joint opening weakening behavior

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Effects of herding behavior of tradable green certificate market players on market efficiency: Insights

Frontiers in Energy 2023, Volume 17, Issue 2, Pages 266-285 doi: 10.1007/s11708-021-0752-1

Abstract: efficiency is reflected in stimulating renewable energy investment, but may be reduced by the herding behaviorheterogeneous agents, communication structure, and regulatory rules to explore the characteristics of herding behaviorThe results show that the evolution of herding behavior reduces information asymmetry and improves marketMoreover, the herding behavior may evolve to an equilibrium where the revenue of market players is comparable

Keywords： tradable green certificate herding behavior evolution heterogeneous agent model complex network

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Adsorption behavior of antibiotic in soil environment: a critical review

Shiliang WANG,Hui WANG

Frontiers of Environmental Science & Engineering 2015, Volume 9, Issue 4, Pages 565-574 doi: 10.1007/s11783-015-0801-2

Abstract: Antibiotics are used widely in human and veterinary medicine, and are ubiquitous in environment matrices worldwide. Due to their consumption, excretion, and persistence, antibiotics are disseminated mostly via direct and indirect emissions such as excrements, sewage irrigation, and sludge compost and enter the soil and impact negatively the natural ecosystem of soil. Most antibiotics are amphiphilic or amphoteric and ionize. A non-polar core combined with polar functional moieties makes up numerous antibiotic molecules. Because of various molecule structures, physicochemical properties vary widely among antibiotic compounds. Sorption is an important process for the environment behaviors and fate of antibiotics in soil environment. The adsorption process has decisive role for the environmental behaviors and the ultimate fates of antibiotics in soil. Multiply physicochemical properties of antibiotics induce the large variations of their adsorption behaviors. In addition, factors of soil environment such as the pH, ionic strength, metal ions, and organic matter content also strongly impact the adsorption processes of antibiotics. Review about adsorption of antibiotics on soil can provide a fresh insight into understanding the antibiotic-soil interactions. Therefore, literatures about the adsorption mechanisms of antibiotics in soil environment and the effects of environment factors on adsorption behaviors of antibiotics in soil are reviewed and discussed systematically in this review.

Keywords： adsorption antibiotics environment factors soil

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Linear viscoelastic behavior of asphalt binders and mixtures containing very high percentages of reclaimed

Frontiers of Structural and Civil Engineering Pages 1211-1227 doi: 10.1007/s11709-023-0983-9

Abstract: The primary aim of this study is to correlate the impact of aggregates, if any, on the viscoelastic behaviorShift-Homothety-Shift in time-Shift (SHStS) transformation was used to compare the linear viscoelastic behaviorThe influence of aggregates on the viscoelastic behavior of asphalt mixtures depends on temperature andThe role of asphalt binders in the behavior of asphalt mixtures is more pronounced at high temperaturesThe maximum difference (60% to 70%) in the viscoelastic behavior of the binder and mixture based on SHStS

Keywords： RAP complex modulus SHStS transformation rejuvenation behavior of asphalt binder and mixture

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Associations of sleeping patterns and isotemporal substitution of other behavior with the prevalence

Frontiers of Medicine doi: 10.1007/s11684-023-1019-5

Abstract: (CKD) risk, but limited research evaluated the association of reallocating excessive sleep to other behaviorCancers in Chinese Diabetic Individuals: A Longitudinal Study, with self-reported time of daily-life behaviorobserved in long sleepers with diabetes than in those with prediabetes, and they benefited from other behaviorThe divergence in the predicted effect on CKD following time reallocation to behavior of different domains

Keywords： sleep physical activity chronic kidney disease isotemporal substitution behavioral pattern

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Microfluidics for cell-cell interactions: A review

Rui Li,Xuefei Lv,Xingjian Zhang,Omer Saeed,Yulin Deng

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 1, Pages 90-98 doi: 10.1007/s11705-015-1550-2

Abstract: The well-designed microscale intermediary is also ideal for the study of cell biology.Particularly, microfluidic chip is helpful for better understanding cell-cell interactions.

Keywords： microfluidic chip co-culture cell-cell interactions review

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Distinct mononuclear diploid cardiac subpopulation with minimal cell–cell communications persists in

Frontiers of Medicine Pages 939-956 doi: 10.1007/s11684-023-0987-9

Abstract: 645 cardiac cells were generated from embryonic day 17.5 and postnatal days 2 and 8 mice by single-cellMNDCMs having interactions with macrophages and non-proliferative MNDCMs (non-pMNDCMs) with minimal cell–cellThese MNDCMs were mapped to the heart by integrating the spatial and single-cell transcriptomic data.In conclusion, a novel non-pMNDCM subpopulation with minimal cell–cell communications was unveiled, highlighting

Keywords： mononuclear diploid cardiomyocytes cell–cell communication cardiac fibroblast single-cell RNA sequencing

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Deubiquitinases as pivotal regulators of T cell functions

Xiao-Dong Yang, Shao-Cong Sun

Frontiers of Medicine 2018, Volume 12, Issue 4, Pages 451-462 doi: 10.1007/s11684-018-0651-y

Abstract: Defect in T cell activation is associated with severe immune deficiencies, whereas aberrant T cell activationAn emerging mechanism that regulates T cell activation and tolerance is ubiquitination, a reversibleIt is now well recognized that DUBs are crucial regulators of T cell responses and serve as potential

Keywords： deubiquitinase ubiquitination T cell activation T cell differentiation T cell tolerance

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Cell surface protein engineering for high-performance whole-cell catalysts

Hajime Nakatani,Katsutoshi Hori

Frontiers of Chemical Science and Engineering 2017, Volume 11, Issue 1, Pages 46-57 doi: 10.1007/s11705-017-1609-3

Abstract: Cell surface protein engineering facilitated by accumulation of information on genome and protein structureinvolves heterologous production and modification of cell surface proteins using genetic engineering, and is important for the development of high-performance whole-cell catalysts.In this field, cell surface display is a major technology by exposing target proteins, such as enzymes, on the cell surface using a carrier protein.

Keywords： cell surface engineering surface display whole-cell catalysts bioprocess

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Uncertainty of concrete strength in shear and flexural behavior of beams using lattice modeling

Frontiers of Structural and Civil Engineering 2023, Volume 17, Issue 2, Pages 306-325 doi: 10.1007/s11709-022-0890-5

Abstract: This paper numerically studied the effect of uncertainty and random distribution of concrete strength in beams failing in shear and flexure using lattice modeling, which is suitable for statistical analysis. The independent variables of this study included the level of strength reduction and the number of members with reduced strength. Three levels of material deficiency (i.e., 10%, 20%, 30%) were randomly introduced to 5%, 10%, 15%, and 20% of members. To provide a database and reliable results, 1000 analyses were carried out (a total of 24000 analyses) using the MATLAB software for each combination. Comparative studies were conducted for both shear- and flexure-deficit beams under four-point loading and results were compared using finite element software where relevant. Capability of lattice modeling was highlighted as an efficient tool to account for uncertainty in statistical studies. Results showed that the number of deficient members had a more significant effect on beam capacity compared to the level of strength deficiency. The scatter of random load-capacities was higher in flexure (range: 0.680–0.990) than that of shear (range: 0.795–0.996). Finally, nonlinear regression relationships were established with coefficient of correlation values (R²) above 0.90, which captured the overall load–deflection response and level of load reduction.

Keywords： lattice modeling shear failure flexural failure uncertainty deficiency numerical simulation